Mark A. Frye, MD
Mark A. Frye, MD, is a consultant in the Department of Psychiatry & Psychology at Mayo Clinic. He joined Mayo in 2006 and holds the academic rank of Professor of Psychiatry, Mayo Clinic College of Medicine and Science, and served as an esteemed chair of the Department of Psychiatry & Psychology for more than a decade.
Born and raised in Rochester, MN, Dr. Frye received his MD from the University of Minnesota and completed his psychiatric training at the Semel Institute for Neuroscience and Human Behavior at the David Geffen School of Medicine at UCLA. He completed a fellowship at the National Institute of Mental Health in Bethesda, MD, with a research focus on the neurobiology of treatment-resistant depression and bipolar disorder.
Dr. Frye’s current research centers on biomarkers of mood disorders and alcoholism. He and his team established the Mayo Clinic Individualized Medicine Biobank for Bipolar Disorder to identify the underpinning mechanisms of bipolar disorder through genomic studies. An active author, he has published more than 380 papers in important peer-reviewed journals, and has received significant research support from several national medical organizations and private foundations focused on mental health.
In addition to serving as a scientific reviewer for NIMH and other significant roles, Dr. Frye serves as the vice chair of the Depression and Bipolar Support Alliance (DBSA) Scientific Advisory Board. He has received numerous awards for his research on mental health.